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抗人eif3g多克隆抗体
- 参考价格： ¥1100.0 - 2310.0
- 品 牌： abgent
- 货 号： AP5342c
- 适应物种： 人
- 应用范围： 免疫印迹,免疫组化,流式细胞技术
- 克 隆 性： 多克隆
- 亚 型： Rabbit Ig
- 抗体类型： 一抗
产品概览
| 背景： | Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. This subunit can bind 18S rRNA.REFERENCESZhou, M., et al. Proc. Natl. Acad. Sci. U.S.A. 105(47):18139-18144(2008)Masutani, M., et al. EMBO J. 26(14):3373-3383(2007)Damoc, E., et al. Mol. Cell Proteomics 6(7):1135-1146(2007) |
| 其他名字： | EIF3G; EIF3S4; Eukaryotic translation initiation factor 3 subunit G; Eukaryotic translation initiation factor 3 RNA-binding subunit; Eukaryotic translation initiation factor 3 subunit 4; eIF-3-delta; eIF3 p42; eIF3 p44 |
产品特性
| 预测型适应物种： | Mouse, Rat, Zebrafish, Bovine, Xenopus |
靶点信息
| 基因id： | 8666 |
| 蛋白名： | EIF3G |
| 胞内定位： | Cytoplasm (By similarity). Nucleus. Cytoplasm, perinuclear region. Note=Colocalizes with AIFM1 in the nucleus and perinuclear region |
| 同义词： | EIF3S4 |
应用与保存
| 稀释浓度： | WB~~1:1000WB~~1:1000IHC~~1:50~100FC~~1:10~50 |
| 注意事项： | EIF3G Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
其他
| 参考文献： | Zhou, M., et al. Proc. Natl. Acad. Sci. U.S.A. 105(47):18139-18144(2008)Masutani, M., et al. EMBO J. 26(14):3373-3383(2007)Damoc, E., et al. Mol. Cell Proteomics 6(7):1135-1146(2007) |
| 保存条件： | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| 标记物： | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| 主要序列号： | O75821 |
| 其他序列号： | Q5RK09,Q9Z1D1,Q6DRC4,Q3ZC12,Q641B2,Q6DJI8,NP_003746.2 |
| 分子量： | 35611 Da |
| 功能： | Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. This subunit can bind 18S rRNA. |
| 规格： | 80 µl (8 western blots) | 价格： | ¥1100.00 |
| 规格： | 400 µl (40 western blots) | 价格： | ¥2310.00 |
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