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参考文献:Chondroitin Sulfate is the Primary Receptor for a Peptide-Modified AAV That Targets Brain Vascular Endothelium In Vivo图1:AAV-GMN has broad tissue tropism. The indicated cell lines were transduced with AAV-GMN encoding an eGFP reporter at an MOI of 105 and 24–48 hours later, transduction was assessed by eGFP fluorescence 图2:AAV-GMN displays broad transduction in regions throughout the brain following direct delivery |