Profiling Genome-Wide Histone Modifications and Variants by ChIPchip on Tiling Microarrays in S. cerevisiae
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Chromatin immunoprecipitation coupled to DNA microarray has become a widely used method to study transcription factors and chromatin structure. Here, we provide a detailed protocol for the localization of the variant histone Htz1 in the S. cerevisiae genome. This protocol can easily be adapted to fit other purposes such as profiling histone modifications.