Use of Intron 40 VNTR I in vWD Gene Tracking
互联网
277
Common alleles or polymorphisms form the basis of human diversity, and some of these polymorphisms closely linked on the same chromosome with a defective gene have been used for gene tracking in many genetic disorders. The success of any linkage analysis also relies on the nature of the polymorphisms used, and the most useful are those that can have a large numbers of alleles.
