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        Less common disorders:L

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        DISEASE AND CAUSES PATHOPHYSIOLOGY SIGNS AND SYMPTOMS
        Lassa fever  
        • Viral infection due to Lassa species
        An epidemic hemorrhagic fever transmitted to humans by contact with infected rodent urine, feces, or saliva.
        • Fever lasts 2 to 3 weeks
        • Exudative pharyngitis
        • Oral ulcers
        • Lymphadenopathy
        • Swelling of face and neck
        • Purpura
        • Conjunctivitis
        • Bradycardia
        • Shock
        • Peripheral collapse
        Latex allergy  
        • Hypersensitivity to products containing natural latex
        Latex protein allergens trigger release of histamine and other mediators of the systemic allergic cascade in sensitized persons.
        • Local dermatitis to anaphylactic reaction
        Legg-Calve-Perthes disease  
        • Caused by congenital or developmental factors
        Ischemic necrosis leads to eventual flattening of the head of the femur due to vascular interruption.
        • Pain in hip and proximal thigh
        • Loss of internal rotation, extension, adduction, and flexion
        Legionnaires' disease  
        • Infection due to gram-negative bacillus, Legionella pneumophila
        Transmission of disease occurs with inhalation of organism carried in aerosols produced by air-conditioning units, water faucets, shower heads, humidifiers, and contaminated respiratory equipment.
        • Dry cough
        • Myalgia
        • GI distress
        • Pneumonia
        • Cardiovascular collapse
        Leprosy  
        • Infection due to Mycobacterium leprae
        Chronic, systemic infection with progressive cutaneous lesions, attacking the peripheral nervous system.
        • Skin lesions
        • Anesthesia
        • Muscle weakness
        • Paralysis
        Lichen planus  
        • Cause unknown
        Benign pruritic skin eruption that usually resolves in 2 to 3 years.
        • Itching
        • Scaly, purple papules with white lines or spots on skin or mouth
        Listeriosis  
        • Infection due to gram-positive bacillus Listeria monocytogenes
        Infection with febrile illness, transmitted by neonates in utero, by inhalation, consumption, or contact with contaminated unpasteurized milk, infected animals, or contaminated sewage, mud, or soil.
        • Fever
        • Meningitis
        • Spontaneous abortion

         

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