Ultrasound Imaging of the Murine Kidney

Ultrasound (US) is the most common and least invasive modality for clinical imaging of the kidney. One important application of US in nephrology is the detection and monitoring of structural changes in the kidney. Recent advances in US technology have facilitated the application of similar techniques to animal models of human disease. We have developed a simple US-based method of detection and quantitation of hydronephrosis in a mouse model of congenital obstructive nephropathy, the megabladder (mgb ) mouse.