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Detection of Hepatitis C Virus RNA by Semiquantitative Reverse-Transcription PCR

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The human hepatitis C virus (HCV) is an RNA virus discovered in 1989 that accounts for the majority of posttransfusion and sporadic non-A non-B hepatitis. More than half of patients with acute HCV infection develop a chronic course that is associated with a high risk of developing liver cirrhosis and hepa-tocellular carcinoma.
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