目前已发表文章中RNAi设计的片段综述
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3025
|
Gene (Ref)
|
Accession #
|
Position from ATG
|
Gene Target
(Comments) |
Cell Line Tested
|
| ß-actin (1) |
NM_001101
|
972-994
|
aatgaagatcaagatcattgc
|
Human HeLa
|
| gamma-actin (1) |
NM_001614
|
8-30
|
aagagatcgccgcgctggtca
|
Human HeLa
|
| AIB1 (estrogen receptor coactivator) (22) | AAAGACUCCUUAGGACCGCUU |
Ishikawa
|
||
| Apaf-1 (31) |
978-998
|
AATTGGTGCACTTTTACGTGA
|
IMR90E1
|
|
| ARC21 (1) |
AF006086
|
181-203
|
aagaatgaagctgataggacc
|
Human HeLa
|
| ATR interacting protein (4) |
AF451323
|
254-274
|
AAGGTCCACAGATTATTAGAT
|
Human HeLa
|
| ATR interacting protein (4) |
AF451323
|
464-484
|
CTAGAGGAACAGAGAAGATCACA
|
Human HeLa
|
| ATR interacting protein (4) |
AF451323
|
867-887
|
AAGAAGAGGCCCAGAAAAGCT
|
Human HeLa
|
| Bcr-abl (32) |
AAGCAGAGUUCAAAAGCCCUU
|
TonB, K562, hematopoetic cells | ||
| Brc-abl (32) |
AAAGCAGAGUUCAAAAGCCCU
|
TonB, K562, hematopoetic cells | ||
| beta-tubulin- mouse neuronal (21) | AF312873 |
AAGACAGAGCCAAGUGGACUC
|
Mouse P19
|
|
| Bruton's tyrosine kinase (Btk) (33) | NM_000061 |
1682-1700
|
AAUUGGUAAACGAUCAAGGAG
|
RBL-2H3, WEHI-231, NALM-6
|
| Bruton's tyrosine kinase (Btk) (33) | NM_000061 |
895-913
|
AAGGGAAAGAAGGAGGUUUCA
|
RBL-2H3, WEHI-231, NALM-6
|
| Bruton's tyrosine kinase (Btk) (33) | NM_000061 |
518-536
|
AAGAAGCUUAAAACCUGGGAG
|
RBL-2H3, WEHI-231, NALM-6
|
| Casein Kinase I epsilon and delta (CKI-epsilon and CKI-delta) (17) |
|
520-538
|
AACUGGGGAAGAAGGGCAACC
|
HEK293
|
| Caspase 1 (34) |
191-211
|
AAGGGGCACAGGCATGCCAAA
|
IMR90E1A
|
|
| Caspase 2 (34) |
94-114
|
AAACAGCTGTTGTTGAGCGAA
|
IMR90E1A
|
|
| hCdc2 (24) |
125-147
|
HeLa
|
||
| Cdc14A (23) |
89-109
|
GCACAGTAAATACCCACTATT
|
HeLa
|
|
| cdk1 (1) |
NM_001786
|
125-147
|
aaggggttcctagtactgcaa
|
Human HeLa
|
| CENP-E (1) |
NM_001813
|
944-966
|
aaactcttactgctctccagt
|
Human HeLa
|
| CHO1 (20) |
|
138-156
|
AAGGUCAGUAAUACAACGGUG
|
CHO
|
| corin, mouse (12) |
|
|
AACCACCGCCCUCCGUGCA
|
HL-5 and 293
|
| Cyclin B1 (5) |
J03166
|
199-217
|
CTCGTACAGCCTTGGGAGACA
|
Xenopus embryo
|
| Cyclin B2 (5) |
J03167
|
252-270
|
ATGTTAAGACTAAGCATGTAC
|
Xenopus embryo
|
| cytoplasmic dynein 1 heavy chain (1) |
U53530
|
509-531
|
aaggccaaggaggcgctggaa
|
Human HeLa
|
| DIP13-alpha (DCC interacting protein) (25) | AAGUGCAGCAACACACCUGAC |
DLD1
|
||
| DIP13-beta (DCC interacting protein) (25) | AAGCAGCACCUCUCCUCCCUU |
DLD1
|
||
| Dishevelled (hDv-1 and hDv-3) (16) |
|
|
AACAAGATCACCTTCTCCGAG
|
A293
|
| hDv-2 (16) |
|
|
AACTTTGAGAACATGAGCAAC
|
A293
|
| Eg5 (1) |
NM_004523
|
1547-1569
|
aactggatcgtaagaaggcag
|
Human HeLa
|
| emerin (1) |
NM_000117
|
628-650
|
aaccgtgctcctggggctggg
|
Human HeLa
|
| eve (11) |
|
|
AACUCCUUGAACGGCAGCCGC
|
Drosophila embryos
|
| hFbw7 (cyclin E ubiquitination) (26) |
713-735
|
see reference
|
HeLa
|
|
| Fortilin (35) |
121-141
|
AAGGUAACAUUGAUGACUCGC
|
U2OS
|
|
| GalTII (galactosyltransferase II) (27) |
65-87
|
AAGCACGCGACGCUGGCGCGC |
HeLa
|
|
| GalTII (galactosyltransferase II) (27) |
|
461-482
|
AAGGCGGACGACGACUCCUUC |
HeLa
|
| GAS41 (1) |
NM_006530
|
327-349
|
aagacctgtaaccctgtatca
|
Human HeLa
|
| Hec-1 (36) | NM_006101 |
1517-1539
|
HeLa-S3
|
|
| HPV E6 (38) |
AAGAGGUAUAUGACUUUGCUU
|
CaSKi, SiHa, NDF, HCT116
|
||
| HPV E7 (38) |
AAAGGAGGAUGAAAUAGAUGG
|
CaSKi, SiHa, NDF, HCT116 | ||
| HtrA2 (28) | AAAACGGCUCAGGAUUCGUGG |
U2OS
|
||
| HtrA2 (28) | AAGGGGAGTTTGTTGTTGCCA |
U2OS
|
||
| HtrA2 (28) | AAGCTTTCCCGATGTTCAGCA | |||
| keratin 18 (1) |
NM_000224
|
1154-1176
|
aagatggcgaggactttaatc
|
Human HeLa
|
| Kinase interacting stathmin (hKIS) (39) |
160-180
|
AAGCAGTTCTTGCCGCCAGGA
|
HEK293
|
|
| Kinase interacting stathmin (mKIS) (39) |
160-180
|
AAGCAGTTCCTGCCTCGGGGA
|
HEK293
|
|
| lamin A (13) |
NM019390
|
260-280
|
GAAGCAGCUUCAGGAUGAGAU
|
Human HeLa S3
|
| lamin A (19) |
|
|
AAGGACCUGGAGGUCUGCUG
|
Hep3B
|
| lamin A/C (1) |
NM_005572
|
608-630
|
aactggacttccagaagaaca
(90% reduction; 2) |
Human HeLa
|
| lamin B1 (1) |
NM_005573
|
672-694
|
aacgcgcttggtagaggtgga
|
Human HeLa
|
| lamin B2 (1) |
M94362
|
1457-1479
|
aagaggaggaggaagccgagt
|
Human HeLa
|
| LAP2 (1) |
NM_003276
|
37-59
|
aaagacaagttgaagagtgag
|
Human HeLa
|
| Mad1 (41) |
AF083811
|
1843-1865
|
See reference
|
HeLa-S3
|
| Mammalian septin (MSF) (44) |
AF189712
|
472-492
|
See reference
|
