Causes and Consequences of Damage to Mitochondria: Morphological Aspects
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In recent years the role played by mitochondria in cellular aging has become the focus of intensive research. The concept that these energy-producing organelles are involved in aging derives from the views of Harman (1 ) and Gerschman (2 ) linking senescence to the damaging effects of free radicals, especially those released in the mitochondrial respiratory chain.
