丁香实验_LOGO
登录
提问
我要登录
|免费注册
点赞
收藏
wx-share
分享

Detection of TGF in Body Fluids and Tissues

互联网

492
Transforming growth factor-β1 (TGF-(β1) is a 25-kDa homodimeric protein secreted by numerous cells including platelets, monocytes, macrophages, epithelial cells, and fibroblasts (1 3 ). Active TGF-(β1 exerts multiple and divergent effects on mesenchymal and epithelial cell cycle regulation (1 ). In addition, TGF-(β1 influences the expression of multiple genes, which act in concert to enhance the synthesis of extracellular matrix components with resulting fibrosis (1 ,2 ). In vitro studies have demonstrated that TGF-(β1 regulates the genetic expression of extracellular matrix components, including fibronectin (FN), the α5β1 fibronectin receptor (FNR), collagen, and proteoglycans (4 7 ).
ad image
提问
扫一扫
丁香实验小程序二维码
实验小助手
丁香实验公众号二维码
扫码领资料
反馈
TOP
打开小程序