- ￥2050 - 3870
- Sino Biological
- 北京
- 10358-H03H
- 2025年08月12日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
-20℃ to -80℃
- 保质期：
12个月
- 英文名：
Recombinant Human TGFBR2 Protein (His & Fc Tag)
- 库存：
99
- 供应商：
北京义翘神州科技股份有限公司
- 规格：
20.00 µg/50.00 µg
| 规格： | 20.00 µg | 产品价格： | ￥2050.0 |
|---|---|---|---|
| 规格： | 50.00 µg | 产品价格： | ￥3870.0 |
TGF-beta RII/TGFBR2重组蛋白|Recombinant Human TGFBR2 Protein (His & Fc Tag)（产品说明）
蛋白名称：Human TGFBR2 Protein (His & Fc Tag)
蛋白构建：A DNA sequence encoding the extracellular domain (Met 1-Asp 159) of human TGFβ receptor 2 (NP_003233.4) was expressed with the fused C-terminal His-tagged Fc region of human IgG1 at the C-terminus.
表达宿主：HEK293 Cells
蛋白纯度：> 97 % as determined by SDS-PAGE
蛋白活性：1. Measured by its ability to inhibit TGF-beta1 activity on Mv-1-lu mink lung epithelial cells. The ED50 for this effect is typically 0.2-3.0 μg/ml in the presence of 1 ng/mL of recombinant human TGF-beta1. 2. Measured by its binding ability in a functional ELISA. Immobilized TGFBR2h (1-166Q)(Cat:10358-H08B) at 10 μg/mL (100 μL/well) can bind TGFB1-His/Biotin (Cat:10804-H08H), the EC50 of human TGFB1-His/Biotin (Cat:10804-H08H) is 120-240 ng/mL.
蛋白内毒素：< 1.0 EU per μg of the protein as determined by the LAL method
预测N端：Ile 24
蛋白分子量：The recombinant human TGFβ R2/Fc is a disulfide-linked homodimeric protein after removal of the signal peptide. The monomer consists of 383 amino acids and predicts a molecular mass of 43.4 kDa. By SDS-PAGE under reducing conditions, the apparent molecular mass of this monomer is approximately 60-65 kDa due to the glycosylation.
蛋白NP号：NP_003233.4
蛋白氨基酸序列：Met1-Asp159
蛋白名称：Human TGFBR2 Protein (His & Fc Tag)
蛋白构建：A DNA sequence encoding the extracellular domain (Met 1-Asp 159) of human TGFβ receptor 2 (NP_003233.4) was expressed with the fused C-terminal His-tagged Fc region of human IgG1 at the C-terminus.
表达宿主：HEK293 Cells
蛋白纯度：> 97 % as determined by SDS-PAGE
蛋白活性：1. Measured by its ability to inhibit TGF-beta1 activity on Mv-1-lu mink lung epithelial cells. The ED50 for this effect is typically 0.2-3.0 μg/ml in the presence of 1 ng/mL of recombinant human TGF-beta1. 2. Measured by its binding ability in a functional ELISA. Immobilized TGFBR2h (1-166Q)(Cat:10358-H08B) at 10 μg/mL (100 μL/well) can bind TGFB1-His/Biotin (Cat:10804-H08H), the EC50 of human TGFB1-His/Biotin (Cat:10804-H08H) is 120-240 ng/mL.
蛋白内毒素：< 1.0 EU per μg of the protein as determined by the LAL method
预测N端：Ile 24
蛋白分子量：The recombinant human TGFβ R2/Fc is a disulfide-linked homodimeric protein after removal of the signal peptide. The monomer consists of 383 amino acids and predicts a molecular mass of 43.4 kDa. By SDS-PAGE under reducing conditions, the apparent molecular mass of this monomer is approximately 60-65 kDa due to the glycosylation.
蛋白NP号：NP_003233.4
蛋白氨基酸序列：Met1-Asp159
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文献和实验该产品被引用文献
1, Ding ZY, et al. Transforming growth factor β induces expression of connective tissue growth factor in hepatic progenitor cells through Smad independent signaling.Cellular signalling, PubMed ID: 23727026
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TGF-beta RII/TGFBR2重组蛋白|Recombinant Human TGFBR2 Protein (His & Fc Tag)
￥2050 - 3870
