VU6000918,2101737-32-8

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。

VU6000918

CAS No. : 2101737-32-8

MCE 国际站：VU6000918

产品活性：VU6000918 是毒蕈碱乙酰胆碱 (M4) 阳性变构调节剂，其对hM4 的EC₅₀ 值为 19 nM。

研究领域：GPCR/G Protein  |  Neuronal Signaling

作用靶点：mAChR

In Vitro: VU6000918 demonstrates statistically significant AHL reversal (18%) from a low oral dose of 0.03 mg/kg and reaches maximal reversal (74%) from a 3 mg/kg dose, with a resulting in vivo plasma EC₅₀ of 74 nM (0.66 nM unbound) based on terminal concentrations measured in the study animals (1.5 hr post-administration of 17j).

相关产品：Bioactive Compound Library Plus  |  GPCR/G Protein Compound Library  |  Neuronal Signaling Compound Library  |  Neurotransmitter Receptor Compound Library  |  Heterocyclic Compound Library  |  Membrane Protein-targeted Compound Library  |  Membrane Receptor-targeted Compound Library  |  Clozapine N-oxide  |  Deschloroclozapine  |  Pilocarpine Hydrochloride  |  Atropine  |  Carbamoylcholine chloride  |  Scopolamine hydrobromide  |  Amitriptyline hydrochloride  |  Olanzapine  |  Methacholine chloride  |  Tiotropium Bromide  |  Xanomeline  |  Mepenzolate bromide  |  Promethazine hydrochloride  |  Propantheline bromide  |  Arecoline hydrobromide  |  Oxotremorine M iodide  |  Dronedarone  |  (S)-(+)-Dimethindene maleate  |  Pirenzepine dihydrochloride  |  DREADD agonist 21  |  Benztropine mesylate  |  Darifenacin hydrobromide  |  Tropicamide

热门产品线：重组蛋白  |  化合物库  |  天然产物  |  荧光染料  |  PROTAC  |  同位素标记物

Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  Dye Reagents  |  PROTAC  |  Isotope-Labeled Compounds