HRP, Streptavidin Labeled

Preparation of Horseradish Peroxidase-Labeled Probes

The direct labeling of nucleic acid probes with horseradish peroxidase (HRP) was first described by Renz at EMBL in 1984 (1 ). The methodology was combined with enhanced chemiluminescence (2 ) (a light producing HRP catalyzed reaction

Labeled Avidin Binding (LAB) Method*

The labeled avidin binding (LAB) method is the latest method to use the avidin-biotin technology. It provides even more sensitivity than either the standard peroxidase-antiperoxidase (PAP) or avidin-biotin complex (ABC) methods see Chapter 20

Photobiotin-Labeled DNA and RNA Hybridization Probes

Nucleic acid hybridization, the formation of a duplex between two complementary nucleotide sequences, is being increasingly utilized in the research laboratory and for the routine diagnosis of disease. Biotin-labeled nucleic acid hybridization