- ￥1900
- Biorigin
- BN40571R
- 2025年12月06日
- IHC-P,
- Human,Mouse,Rat,Horse,
企业认证
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 适应物种：
Human,Mouse,Rat,Horse,
- 应用范围：
IHC-P,
- 抗体英文名：
KLK9
- 规格：
100ul
| 英文名称 | KLK9 |
| 中文名称 | 激肽释放酶9抗体（舒血管素9） |
| 别 名 | Kallikrein 8; Kallikrein 9; Kallikrein L3; Kallikrein Like 3; Kallikrein like protein 3; kallikrein related peptidase 9; Kallikrein-9; Kallikrein-like protein 3; Kallikrein8; Kallikrein9; KLK 8; KLK 9; KLK L3; KLK-L3; KLK8; KLK9; KLK9_HUMAN; KLKL 3; KLKL3. |
| 研究领域 | 肿瘤 细胞生物 信号转导 激酶和磷酸酶 细胞骨架 细胞外基质 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Mouse, (predicted: Human, Rat, Horse, ) |
| 产品应用 | ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 26kDa |
| 细胞定位 | 分泌型蛋白 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human KLK9:51-150/250 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 产品介绍 | Kallikrein 9, also known as Kallikrein-Like 3 (KLK-L3), is a chymotrypsin-like serine proteinase. Kallikrein 9 was discovered as the locus for kallikreins on chromosome 19 was more fully mapped and found by similarity to the other tissue kallikreins. Kallikrein 9 has been found in the ovary, thymus, testis, prostate, skin, breast and neuronal tissues and is made by many cell lines in culture. Kallikrein 9 levels in breast cancer and uterine cancer patients have been reported to drop as the disease progresses, thus hK9 might be considered a favorable prognostic marker. Different splice variants of hK9 have been reported, although it is not yet known if they produce functional proteins. The full length Kallikrein 9 encodes for a 250 amino acid protein, with a predicted mass of 27.5 kDa and a pI of 7.53. The 234 amino acid form predicts a protein of 26 kDa with a pI of 9.76 and this quite basic pI might give the shorter form a very different function or localization. The shorter sequence also diverges before the catalytic serine residue, making it unlikely to be proteolytically active. Pre-pro-kallikrein 9 has the 17 amino acid signal sequence is removed before secretion, and the Pro-kallikrein 9 is activated to Kallikrein 9 by removal of the 5 amino acid propeptide domain. Subcellular Location: Secreted (Probable). Tissue Specificity: Skin, thymus, trachea, cerebellum and spinal cord. Similarity: Belongs to the peptidase S1 family. Kallikrein subfamily. Contains 1 peptidase S1 domain. SWISS: Q9UKQ9 Gene ID: 284366 Database links: Entrez Gene: 284366 Human Omim: 605504 Human SwissProt: Q9UKQ9 Human Unigene: 448942 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. KLK9目前认为是卵巢癌 宫颈癌 子宫内膜癌等其他肿瘤,很有意义的标志物。激肽释放酶KLK是激肽系统的主要限速酶，它是一组存在于多数组织和体液中的丝氨酸蛋白酶，是一种肽链内切酶。KLK又称血管舒缓素，包括15个家族成员。在不同的组织中广泛表达,具有蛋白水解酶的活性。它特异性的在碳末端切割底物肽，可裂解激肽原释放具有活性的激肽，由激肽发挥对心血管系统及肾脏功能的调节作用。 组织KLK是一个大的基因家族，主要分布在肺、肾、血管、脑、肾上腺组织，为一种中等大小的糖蛋白。 |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验人激肽释放酶8(KLK-8) 酶联免疫分析（ELISA ） 试剂盒使用说明书 本试剂仅供研究使用 目的：本试剂盒用于测定人血清，血浆及相关液体样本中激肽释放酶8(KLK-8) 的 含量。 实验原理： 本试剂盒应用双抗体夹心法测定标本中人激肽释放酶 8(KLK-8) 水平。用纯化的人激肽释放酶 8(KLK-8) 抗体包被微孔板，制成固相抗体，往包被单抗的微孔中依次加入激肽释放酶 8(KLK
与激肽生成有关的蛋白酶。EC3． 4． 21． 8。广泛存在于血浆和组织中。可从狗的胰脏中提取出来，但从人、牛、马、狗、猫等的腮腺、颌下腺、舌下腺等也能获得同样的物质。虽不引起正常动物的血糖量的变化，但具有使切除胰脏的狗或人的糖尿病患者的血糖量降低的作用。它与胰岛素是不同的物质，口服也有效。
人激肽释放酶1(KLK-1) 酶联免疫分析（ELISA ） 试剂盒使用说明书 本试剂仅供研究使用 目的：本试剂盒用于测定人血清，血浆及相关液体样本中激肽释放酶1(KLK-1) 的 含量。 实验原理： 本试剂盒应用双抗体夹心法测定标本中人激肽释放酶 1(KLK-1) 水平。用纯化的人激肽释放酶 1(KLK-1) 抗体包被微孔板，制成固相抗体，往包被单抗的微孔中依次加入激肽释放酶 1(KLK
技术资料暂无技术资料 索取技术资料
