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- 文献和实验
- 技术资料
- 保存条件：
Powder: -20°C, 3 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 英文名：
Mulberroside D
- 库存：
货期：询盘
- 供应商：
MedChemExpress LLC
- CAS号：
166734-06-1
- 规格：
1 mg
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cis-Mulberroside A
CAS No. : 166734-06-1
MCE 国际站：cis-Mulberroside A
产品活性：cis-Mulberroside A (Mulberroside D) 是 Mulberroside A 的顺式异构体。Mulberroside A 是桑树 (Morus alba L.) 中的主要生物活性成分之一。Mulberroside A 可降低 TNF-α，IL-1β 和 IL-6 的表达，抑制 NALP3，caspase-1 和 NF-κB 的激活以及 ERK，JNK 和 p38 的磷酸化 。Mulberroside A 具有抗炎和抗细胞凋亡作用。Mulberroside A 对蘑菇酪氨酸酶 ( tyrosinase) 具有抑制活性，IC50 为 53.6 μM。
研究领域：Apoptosis | Immunology/Inflammation | Metabolic Enzyme/Protease
作用靶点：TNF Receptor | Interleukin Related | Tyrosinase
In Vivo: Mulberroside A (10, 20, and 40 mg/kg) decreases serum uric acid levels and increases urinary urate excretion and fractional excretion of uric acid in hyperuricemic mice.
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