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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
- 保质期:
Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
- 英文名:
Recombinant Human Glial cell line-derived neurotrophic factor (GDNF)
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 规格:
1mg/100μg/20μg
| 规格: | 1mg | 产品价格: | ¥11868.0 |
|---|---|---|---|
| 规格: | 100μg | 产品价格: | ¥3510.0 |
| 规格: | 20μg | 产品价格: | ¥2340.0 |
纯度:
Greater than 90% as determined by SDS-PAGE.基因名:
GDNFUniprot No.:
P39905别名:
Astrocyte-derived trophic factor ;ATF种属:
Homo sapiens (Human)蛋白长度:
Full Length of Mature Protein来源:
E.coli分子量:
15.1 kDa表达区域:
78-211aa氨基酸序列:
SPDKQMAVLPRRERNRQAAAANPENSRGKGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKEELIFRYCSGSCDAAETTYDKILKNLSRNRRLVSDKVGQACCRPIAFDDDLSFLDDNLVYHILRKHSAKRCGCI蛋白标签:
Tag-Free产品提供形式:
Liquid or Lyophilized powder缓冲液:
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.货期:
13-23 business days注意事项:
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.功能:
Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.内毒素:
Not test.SDS-PAGE:
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.LC-MS Image Description/Western Blot:
/Product types:
Developed ProteinBiological_Activity:
/Research Areas:
NeuroscienceReconstitution:
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.Reference:
GDNF a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons.Lin L.-F.H., Doherty D.H., Lile J.D., Bektesh S., Collins F.Science 260:1130-1132(1993)Function:
Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Culture of Purified Glial Cell Populations from Optic Nerve
Glial cells play a key role in nervous system function, providing neurotrophic factor support to neurons as well as taking part in two-way neuron-glia signaling (e.g., neurotransmitter release). White matter-derived glia are important
脂肪燃烧的指令从哪里来?Nature 揭示神经免疫互作如何与
表明神经-间充质细胞之间的信号能够调节内脏脂肪的 ILC2s。图片来源:Nature间充质来源的 GDNF(glial-derived neurotrophic factor)调控 ILC2s为了研究神经-间充质相互作用是如何调节 ILC2s 的激活,他们对来自 6-OHDA 处理小鼠和对照组小鼠的 PDGFRA 阳性 MSCs 进行了全转录组分析。发现 Gdnf 在 PDGFRA 阳性 MSCs 中高表达,而 6-OHDA 处理则可显著降低其表达。与上述结果一致的是,Adrb2 敲除小鼠的内脏
Expression of Neurotrophic Factors such as GDNF in the E. coli System
neurotrophic factor (BDNF), neurotrophin-3 (NT-3), NT-4/5, glial-cell-line-derived neurotrophic factor (GDNF), ciliary neurotrophic factor (CNTF), insulin-like growth factor-1 (IGF-I), are currently in clinical trials and have potential
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