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- Cell Signaling(CST)
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- 2025年07月15日
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文献和实验Tissue-Specific Knockout of Androgen Receptor in Mice
Androgen acting through the androgen receptor (AR) is known to be essential for male sexual differentiation and development. Using Cre -lox technology, we have generated the floxed AR mice, which have been bred with general or tissue-specific
Analysis of Ligand-Specific Co-repressor Binding to the Androgen Receptor
antihormones (antagonists) for the androgen receptor (AR) is mediated by enhanced recruitment and activity of co-repressors that cause repression of AR target genes that regulate proliferation and alteration of cancer cells. Therefore co-repressor recruitment
Analysis of Androgen Receptor SUMOylation
Androgen receptor (AR) is a ligand-controlled transcription factor that is deregulated and therefore targeted in prostate cancer. In addition to androgens, AR is regulated by post-translational modifications (PTMs). SUMOylation, conjugation
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