- ￥4800
- Tanda
- 美国
- TD-26338
- 2025年10月27日
- ELISA, WB, IHC
- Mouse
- 脊椎动物
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
A synthetic peptide from the internal region of RHEB which includes the mutation of Y35N, human origin.
- 亚型：
lgG
- 形态：
液体
- 保存条件：
-20℃
- 克隆性：
单克隆
- 标记物：
FITC
- 适应物种：
脊椎动物
- 保质期：
24个月
- 抗原来源：
蛋白
- 目录编号：
TD-26338
- 级别：
科研级
- 库存：
999
- 供应商：
武汉天德
- 宿主：
Mouse
- 应用范围：
ELISA, WB, IHC
- 浓度：
1mg/ml
- 靶点：
Y35N
- 抗体英文名：
Anti RHEB(Y35N) Mouse Monoclonal Antibody
- 抗体名：
RHEB(Y35N)
- 规格：
100 μL
RheB(Y35N)
| Cat. #: TD-26338 |
| Size: 100 µL |
| Gene Symbol: RHEB |
| Description: Anti-RheB(Y35N) Mouse Monoclonal Antibody |
| Background: RheB (Ras Homolog Enriched in Brain) is an evolutionarily conserved member of the Ras-family of small GTP-binding proteins originally found to be rapidly induced by synaptic activity in the hippocampus following seizure. While it is expressed at relatively high levels in the brain, RheB is widely expressed in other tissues and may be induced by growth factor stimulation. RheB has an important role in regulating the insulin/TOR signaling pathway. The mammalian target of rapamycin, mTOR, is a serine/threonine protein kinase that acts as a sensor for ATP and amino acids, balancing the availability of nutrients with translation and cell growth. The tuberin/hamartin (TSC2/TSC1) complex inhibits mTOR activity indirectly by inhibiting RheB via tuberin’s GAP activity. |
| Immunogen: A synthetic peptide from the internal region of RHEB which includes the mutation of Y35N, human origin. |
| Applications: ELISA, WB, IHC |
| Recommended Dilutions: ELISA: 1:1000-1:2000 WB: 1:500-1:1000 IHC: 1:50-1:100 |
| Concentration: 1 mg/ml |
| Host Species: Mouse |
| Format: Liquid |
| Clonality: Monoclonal |
| Isotype: IgG |
| Purity: Purified from ascites |
| Preservative: No |
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Species Reactivity: Recognizes Y35N mutant, but not wild type RHEB of vertebrates. |
| Storage Conditions: Store at -20°C. Avoid repeated freezing and thawing |
Western blot:
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Immunofluorescence:
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文献和实验仪上观察照相记录。 1．4 数据处理 （1）相似系数度量鲮鱼的遗传差异水平 任意两个个体间（居群）的遗传距离（D）根据两个个体（居群）共享RAPD 标记来计算： D＝1－S xy ，S xy ＝2N xy /N x ＋N y ） D 是遗传距离，Sxy 为第x 和y 个体（居群）的相似系数，N x 和N y
癌症、糖尿病与心血管疾病。 小G蛋白Rheb(Ras homolog enriched in brain)是mTOR信号通路 的关键调节蛋白，虽然调控Rheb的GTP水解酶激活蛋白(GAP)很早被发现，但是其鸟嘌呤交换因子(GEF)一直没有被鉴定出来。最近有实验表明果蝇的TCTP(translationally controlled tumor protein) 对TOR信号传导通路有调控作用，有可能是Rheb的GEF。小鼠和拟兰芥中的遗传学实验表明TCTP对于细胞生长也有重要
. ，H e ，G . ，C h a n g ，J . ，L i ，K. a n d Y a n g ， G. (2 Q (Y 7 ) O p tim iza tio n o f w h ea t co -tra n sfo rm a lio n p ro ced u re w ith g en e cassettes resu lted in a n im p ro vem en t in tra n sfo rm a tio n freq u en cy. Mol
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