Protocadherin Gamma-A8 (PCDHGA

产品名称：Protocadherin Gamma-A8 (PCDHGA8) Antibody-Protocadherin Gamma-A8 (PCDHGA8) Antibody

产品货号：abx026557

产品规格：80ul#400ul

应用类型：WB, IHC, IF/ICC

保存建议：Protocadherin Gamma-A8 (PCDHGA8) Antibody-Protocadherin Gamma-A8 (PCDHGA8) Antibody建议收到产品后，储存温度为-20°C。避免重复冻融

背景资料：This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

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关键词：Protocadherin Gamma-A8 (PCDHGA8) Antibody，Protocadherin Gamma-A8 (PCDHGA8) Antibody，待更新