Ryanodine Receptor 2 (RYR2) An

产品名称：Ryanodine Receptor 2 (RYR2) Antibody-Ryanodine Receptor 2 (RYR2) Antibody

产品货号：abx000677

产品规格：20ul#50ul#100ul#200ul

应用类型：WB, IHC

保存建议：Ryanodine Receptor 2 (RYR2) Antibody-Ryanodine Receptor 2 (RYR2) Antibody建议收到产品后，储存温度为-20°C。避免重复冻融

背景资料：RYR2 Antibody is a Rabbit Polyclonal antibody against RYR2. RYR2 belongs to the ryanodine receptor family. RYR2 provides communication between transverse-tubules and sarcoplasmic reticulum. Contraction of cardiac muscle is triggered by release of calcium ions from SR following depolarization of T-tubules. Defects in RYR2 are the cause of familial arrhythmogenic right ventricular dysplasia type 2 (ARVD2) which known as arrhythmogenic right ventricular cardiomyopathy 2 (ARVC2). Defects in RYR2 are the cause of catecholaminergic polymorphic ventricular tachycardia type 1 (CPVT1) which known as stress-induced polymorphic ventricular tachycardia (VTSIP). This gene encodes a ryanodine receptor found in cardiac muscle sarcoplasmic reticulum. The encoded protein is one of the components of a calcium channel, composed of a tetramer of the ryanodine receptor proteins and a tetramer of FK506 binding protein 1B proteins, that supplies calcium to cardiac muscle. Mutations in this gene are associated with stress-induced polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia. [provided by RefSeq, Jul 2008].

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关键词：Ryanodine Receptor 2 (RYR2) Antibody，Ryanodine Receptor 2 (RYR2) Antibody，待更新