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- 详细信息
- 文献和实验
- 技术资料
- 品牌：
pLightSwitch
- 货号：
S803752
- 产地：
美国
- 库存：
大量
- 供应商：
switchgear
| Product ID | S803752 |
| Vector name | pLightSwitch_3UTR |
| Gene symbol | BAD |
| Insert length | 500 |
| Restriction pair | NHE1XHO1 |
| NOTE | The sequence below is sequence from the reference human genome. The actual cloned fragment may contain SNPs or other naturally occurring sequence variants. |
| Sequence | GTCTTCCAGTCCTGGTGGGATCGGAACTTGGGCAGGGGAAGCTCCGCCCCCTCCCAGTGA CCTTCGCTCCACATCCCGAAACTCCACCCGTTCCCACTGCCCTGGGCAGCCATCTTGAAT ATGGGCGGAAGTACTTCCCTCAGGCCTATGCAAAAAGAGGATCCGTGCTGTCTCCTTTGG AGGGAGGGCTGACCCAGATTCCCTTCCGGTGCGTGTGAAGCCACGGAAGGCTTGGTCCCA TCGGAAGTTTTGGGTTTTCCGCCCACAGCCGCCGGAAGTGGCTCCGTGGCCCCGCCCTCA GGCTCCGGGCTTTCCCCCAGGCGCCTGCGCTAAGTCGCGAGCCAGGTTTAACCGTTGCGT CACCGGGACCCGAGCCCCCGCGATGCCCTGGGGGCCGTGCTCACTACCAAATGTTAATAA AGCCCGCGTCTGTGCCGCCGAGGCTTTTCTGTGCGTCGACTGGGGCTCCGGCAGGCCGGG GTAGTGCTCTCACGGATACT |
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文献和实验pathways. We detected significant levels of Bad in the mitochondria of monocytes/macrophages and found that these signaling pathways converge in Bad phosphorylation, and thus in its cytosolic accumulation. Phosphorylation inhibits binding of Bad to Bcl
-1R may be involved in the proliferation of transformed cells, making inhibition of IGF-1R signaling a strategy for the development of cancer drugs. IGF-1R activates three signaling pathways that converge to phosphorylate BAD protein and block apoptosis
-1R may be involved in the proliferation of transformed cells, making inhibition of IGF-1R signaling a strategy for the development of cancer drugs. IGF-1R activates three signaling pathways that converge to phosphorylate BAD protein and block apoptosis
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