- ￥960 - 1600
- Solarbio
- 北京
- K108665P
- 2025年07月12日
- WB IHC
- Rabbit
- Human Mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
A synthetic peptide of Human WWTR1
- 亚型：
IgG
- 形态：
液体
- 保存条件：
低温
- 克隆性：
Polyclonal Antibody
- 标记物：
WWTR1
- 适应物种：
Human Mouse
- 保质期：
标签为准
- 目录编号：
25937
- 库存：
99
- 供应商：
北京索莱宝科技有限公司
- 宿主：
Rabbit
- 应用范围：
WB IHC
- 浓度：
现询客服
- 抗体英文名：
Anti-WWTR1 Polyclonal Antibody
- 抗体名：
TAZ;WW domain containing transcription regulator 1
- 规格：
50ul/100ul
| 规格： | 50ul | 产品价格： | ￥960.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1600.0 |
| 英文名称 | Anti-WWTR1 Polyclonal Antibody |
| 宿主 | Rabbit |
| 别名 | TAZ;WW domain containing transcription regulator 1 |
| 稀释比例 | WB 1:1000-3000. IHC 1:50-200. |
| 蛋白分子量 | 44kDa |
| Gene ID | 25937 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of Human WWTR1 |
| 亚细胞定位 | Nucleus Cytoplasm |
| Swiss Prot | Q9GZV5 |
| 背景资料 | Transcriptional coactivator which acts as a downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. WWTR1 enhances PAX8 and NKX2-1/TTF1-dependent gene activation. Regulates the nuclear accumulation of SMADS and has a key role in coupling them to the transcriptional machinery such as the mediator complex. Regulates embryonic stem-cell self-renewal, promotes cell proliferation and epithelial-mesenchymal transition. |
| Public Immunogen Range | 280-330/400aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | Human Mouse |
| 应用 | WB IHC |
| 规格 | 50ul 100ul |
备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
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文献和实验Polyclonal Antibody Production
, if desired this is best accomplished by Protein A Affinity Chromatography. 上一篇：make an Antibody against a Peptides 下一篇：Immunization Protocol for Monoclonal Antibody Production
Polyclonal Antibody Production
Polyclonal Antibody Production Very useful for rapid and simple generation of antibodies for western blots, ELISA assays, and immunoprecipitation. Rabbit Immunization Initial Preparation Your antigen
a simple ELISA method to detect human anti-antibody response.
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