- 询价
- MAB1598
- 2025年07月14日
- Western Blotting;Immunocytochemistry
- Mouse
- Rat
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- 详细信息
- 技术资料
- 应用范围：
Western Blotting;Immunocytochemistry
- 宿主：
Mouse
- 适应物种：
Rat
- 抗原来源：
0
- 库存：
大量
- 是否单克隆：
1
- 规格：
100 μg
| Species Reactivity | Key Applications | Host | Format | Antibody Type |
|---|---|---|---|---|
| H, M, R | IC, IP, WB | Mouse | Purified | Monoclonal Antibody |
Description:
Anti-Post Synaptic Density Protein 95, clone 7E3-1B8
Background Information:
The postsynaptic density (PSD) is an electron dense structure just beneath the postsynaptic membrane. Several functions have been proposed for the PSD including regulating receptor number and clustering, anchoring signal transduction molecules at the synapse and mediating adhesion between the presynaptic and postsynaptic membranes. The most abundant PSD protein is the [alpha] subunit of the type II calcium/calmodulin dependent protein kinase ([alpha]CaMKII). This protein is likely to play a role in the calcium-mediated signal transduction at the synapse that mediates certain forms of synaptic plasticity. Another major PSD protein is PSD-95, a member of the guanylate kinase family (GUK) of proteins.
Alternate Names:
PSD-95
Clone:
7E3-1B8
Specificity:
Reacts with recombinant rat PSD-95 and identifies a band at approximately ~100 kDa, corresponding to PSD-95, on western blots of rat brain, mouse brain and bovine brain extracts. Also present in rat brain and mouse brain tissue extracts are bands of approximately 80 kDa and 50 kDa. PSD-95 is believed to initiate NMDA receptor clustering on the post synaptic membrane.
Key Applications:
- Immunocytochemistry
- Immunoprecipitation
- Western Blotting
Application Notes:
Immunocytochemistry:
A previous lot of this antibody was used in IC.
Immunoprecipitation:
A previous lot of this antibody was used in IP.
Optimal working dilutions must be determined by the end user.
A previous lot of this antibody was used in IC.
Immunoprecipitation:
A previous lot of this antibody was used in IP.
Optimal working dilutions must be determined by the end user.
Species Reactivity:
- Human
- Mouse
- Rat
Species Reactivity Note:
Mouse and rat. Expected to react with human based on sequence homology
Isotype:
IgG2a
Immunogen:
Recombinant rat PSD-95
Molecular Weight:
~ 95 kDa
Control:
Mouse brain, rat brain tissue
Presentation:
Purified moust monoclonal IgG2a liquid in buffer containing PBS, pH 7.2, with 0.09% sodium azide and 50% glycerol.
Storage Conditions:
Stable for 1 year at -20ºC from date of receipt.
Quality Assurance:
Evaluated by Western Blot on Mouse brain lysates.
Western Blot Analysis:
1:500 dilution of this antibody detected PSD-95 on 10 µg of Mouse brain lysates.
Western Blot Analysis:
1:500 dilution of this antibody detected PSD-95 on 10 µg of Mouse brain lysates.
Antibody Category:
Neuroscience
Antibody Sub-Category:
Synapse & Synaptic Biology
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Trade Name:
Chemicon (Millipore)
Format:
Purified
Host:
Mouse
Concentration:
1 .0 mg/mL
Antibody Type:
Monoclonal Antibody
更多产品技术资讯，请访问密理博中国博客：http://blog.milliporechina.com
Recombinant rat PSD-95 详细描述见链接：http://www.millipore.com/catalogue/item/MAB1598
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PSD-95单克隆抗体 WB/IC/IP适用 psd-95 antibody
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