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文献和实验Manipulation of Early Region 4
of the functions of E4 products is summarized below. Fig. 1 A ) The organization of adenovirus early region 4 E4 open reading frames (ORFs) are indicated by open boxes above a scale that indicates position in map units (0 to 100; 1 map
Generation of Antibody Molecules Through Antibody Engineering
domains of the heavy (V H ) and light (V L ) chains. Effector functions are determined by constant C H 2 and C H 3 domains. The picture is based on the crystal structure of an intact IgG2 anti-canine lymphoma MAb231 ( 2 ) (pdb entry 1IGT). The drawing
Combined 3C-ChIP-Cloning (6C) Assay: A Tool to Unravel Protein-Mediated Genome Architecture
involves conventional 3C methodology: The chromatin is cross-linked, digested with restriction enzymes, and ligated under conditions that favor intramolecular ligation. Immediately after ligation, the chromatin is immunoprecipitated using an antibody
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