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Assays of Matrix Metalloproteinases (MMPs) and MMP Inhibitors: Bioassays and Immunoassays Applicable to Cell Culture Medium, Serum, and Synovial Fluid

The metalloproteinases (MMPs) are a diverse family of enzymes that, together, are capable of degrading all the constituents of the extracellular matrix (ECM). They are required for normal development and for general turnover of the ECM

ECM and FGF-Dependent Assay of Embryonic SMG Epithelial Morphogenesis: Investigating Growth Factor/Matrix Regulation of Gene Expression During Submand

Epithelial-mesenchymal interactions during organogenesis are regulated by dynamic and reciprocal interactions between growth factors and extracellular matrix (ECM) components. Mouse embryonic submandibular gland (SMG) epithelium, isolated

Isolation and Long-Term Maintenance of Adult Rat Hepatocytes in Culture

to be particularly well-suited, since it exhibits in vivo-like ECM geometry, has relatively flexible medium requirements, and individual cell morphology and structure can be easily visualized. One disadvantage, however, is that, in current practice, the ECM layer