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- 技术资料
- 保存条件:
详询
- 保质期:
12 months from date of receipt.
- 英文名:
BIOTIN-PEG4-SBP1(spike-binding peptide 1)
- 库存:
99
- 供应商:
Biorbyt
- 规格:
5 mg
类别: Small Molecules
描述: Biotin modification of SBP1.SBP1(spike-binding peptide 1) is a first-in-class peptide binder to the SARS-CoV-2 spike protein. SBP1 specifically binds SARS-CoV-2-RBD with low nanomolar affinity. SBP1 to the RBD was determined to be 47 nM with the average Kon = 4.69*104M-1S-1 and Koff=2.2*10-3.The interaction between SBP1 and the RBD of SARS-CoV-2 spike protein was validated by bio-layer interferometry. The KD, derived from protein association and dissociation kinetics, was found to be 47 nM after averaging the fitting values at different protein concentrations. The amino acid sequence of SBP1 is entirely derived from human ACE2 and should be recognized as endogenous by the human immune system. This feature could be highly beneficial in later stages of pre-clinical development.
分子式: BIOTIN-PEG4-IEEQAKTFLDKFNHEAEDLFYQS
分子量: 3273.55
纯度: >98%
备注: For research use only.
描述: Biotin modification of SBP1.SBP1(spike-binding peptide 1) is a first-in-class peptide binder to the SARS-CoV-2 spike protein. SBP1 specifically binds SARS-CoV-2-RBD with low nanomolar affinity. SBP1 to the RBD was determined to be 47 nM with the average Kon = 4.69*104M-1S-1 and Koff=2.2*10-3.The interaction between SBP1 and the RBD of SARS-CoV-2 spike protein was validated by bio-layer interferometry. The KD, derived from protein association and dissociation kinetics, was found to be 47 nM after averaging the fitting values at different protein concentrations. The amino acid sequence of SBP1 is entirely derived from human ACE2 and should be recognized as endogenous by the human immune system. This feature could be highly beneficial in later stages of pre-clinical development.
分子式: BIOTIN-PEG4-IEEQAKTFLDKFNHEAEDLFYQS
分子量: 3273.55
纯度: >98%
备注: For research use only.
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BIOTIN-PEG4-SBP1(spike-binding peptide 1),orb654591,Biorbyt
¥12168










