- ￥21480
- TargetMol
- 美国
- TP1979
- 2025年07月07日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
零下80~20°C
- 保质期：
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名：
NLS-StAx-h
- 库存：
10
- 供应商：
TargetMol
- CAS号：
TP1979
- 规格：
5 mg
Product Introduction
Bioactivity
英文名:NLS-StAx-h
描述:Wnt inhibitor (IC50 = 1.4 μM). Stapled peptide inhibitor of oncogenic Wnt signaling. Inhibits β-catenin-transcription factor interactions. Inhibits proliferation and migration of colorectal cancer cells. Cell permeable.
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文献和实验-Gal by adenovirus in vivo and in vitro [38]. Furthermore, the linking of the SV40 nuclear localization signal (NLS) peptide sequence (PKKKRKV) via PNA to a reporter gene that carried the vector, transfecting cells and polyethylenimine (PEI) resulted
v468.chapter 1 经典 Wnt/b-Catenin 信号通路 （英文完整版）
for achievingthe efficient activation of Wnt target genes and ensuring theappropriate physiological response. Exactly how this is achievedremains somewhat of a mystery. Its nuclear import appears independentof the nuclear localization signal (NLS)/importin
Quantitative immunoprecipitation of GFP-fusion proteins using the GFP-Trap
, which cannot be achieved with conventional antibodies even after 12 h of incubation. Moreover, after precipitation with the GFP-Trap only the antigen (GFP) was detectable on a coomassie gel whereas the typical antibody fragments (light chain, 25 kDa; heavy chain, 50 kDa
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