Iberin

一种天然异硫氰酸酯，可诱导II期解毒酶的表达并激活Nrf2，促进抗氧化剂和II期基因的表达；作为群体感应抑制剂，阻断铜绿假单胞菌中的酰基高丝氨酸内酯信号传导而不影响生长（IC50=31-62μM）。A natural isothiocyanate which induces the expression of phase II detoxification enzymes and activates Nrf2, promoting the expression of antioxidant and phase II genes; acts as a quorum sensing inhibitor, blocking acyl-homoserine lactone signaling in P. aeruginosa without affecting growth (IC50 = 31-62 μM).