KH7

sAC的选择性抑制剂，IC50值在3-10µM之间；在50µM时降低精子中基础cAMP的积累；用于多种研究应用，包括哺乳动物卵子受精所需的cAMP介导信号事件、sAC对肾脏中Na+转运的调节以及响应各种应激刺激而导致的线粒体依赖性细胞凋亡。A selective inhibitor of sAC with an IC50 value between 3-10 µM; decreases basal cAMP accumulation in sperm at 50 µM; used in diverse research applications including cAMP-mediated signaling events required for mammalian egg fertilization, sAC regulation of Na+ transport in the kidney, and mitochondrial-dependent apoptosis in response to various stress stimuli.