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SIRT3 (human, recombinant)

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  • ¥1
  • Cayman已认证
  • 10011194-100 µg
  • 2025年07月12日
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    来源:从大肠杆菌中纯化的活性重组N端His标记酶氨基酸101-399;分子量:37kDa(理论值);33.5kDa(实测值);氨基酸:2-399(全长);SIRT3是一种线粒体蛋白,合成时为酶促无活性蛋白。人类SIRT3由基质加工肽酶激活。SIRT3的组成性表达促进PGC-1α、UCP1和其他参与线粒体功能的基因的表达,表明SIRT3调节BAT中的适应性产热。Source: Active recombinant N-terminal His-tagged enzyme amino acids 101-399 purified from E. coli; MW: 37 kDa (theoretical); 33.5 kDa (observed); Amino acids: 2-399 (full length); SIRT3, is a mitochondrial protein that is synthesized as an enzymatically inactive protein. Human SIRT3 is activated by a matrix-processing peptidase. The constitutive expression of SIRT3 promotes the expression of PGC-1α, UCP1, and other genes involved in mitochondrial functions, indicating that SIRT3 modulates adaptive thermogenesis in BAT.

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