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Anti-Na<sup>+</sup>/K<sup>+</s

up> ATPase α-1; 150 μg
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  • 询价
  • 06-520
  • 2025年07月13日
  • Immunoprecipitation;Western Blotting
  • Rabbit
  • Bovine;Rat
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 应用范围：

      Immunoprecipitation;Western Blotting

    • 宿主：

      Rabbit

    • 抗原来源：

      0

    • 适应物种：

      Bovine;Rat

    • 库存：

      大量

    • 是否单克隆：

      2

    • 规格：

      150 μg

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    WB: Rat kidney microsome extract probed with anti-Na+ /K+ ATPase α-1

    Immunoprecipitation Analysis:
    Cat. # 06-520 detects Na+/K+ ATPase at 1:500 dilution in 500 µg of rat brain microsomal prep. lysate.

    Immunohistochemistry: Na/K ATPase (Polyclonal) representative staining pattern/morphology in normal lung epithelium (Top Left), hyperplastic prostate tissue (Top RIght) and human skin tissue (Bottom).

    Species Reactivity Key Applications Host Format Antibody Type
    B, R, H IC, IP, WB Rabbit Purified Polyclonal Antibody
    Description:
    Anti-Na+ /K+ ATPase α-1
    Background Information:
    Na+/K+ ATPase α-1 is a human gene and functions to maintain Na+ and K+ across the cell membrane which is important for osmoregulation. It is a component of (Na+/K+) ATPase, a transporter that catalyzes the hydrolysis of ATP and transports sodium and potassium ions across the plasma membrane. It also partners with Src and other signaling proteins. Binding of ouabain and other cardiotonic steroids to the (Na+/K+) ATPase activates Src, resulting in the assembly and activation of multiple signaling cascades. Binding of ouabain also induces a positive inotropic effect. Diseases associated with ATPase are Thyrotoxic periodic paralysis and hyperthyroidism. (References: Wikipedia and http://www.bioportfolio.com/gene/476-ATP1A1.html)
    Specificity:
    Recognizes the α-1 subunit isoform of Na+ /K+ ATPase.
    Key Applications:
    • Immunocytochemistry
    • Immunoprecipitation
    • Western Blotting
    Species Reactivity:
    • Bovine
    • Rat
    • Human
    Species Reactivity Note:
    Rat and Human. Expected to cross-react with Rat-100%, Mouse-99%; human, pig, rabbit, monkey-96%.
    Isotype:
    IgG
    Immunogen:
    GST-tagged ATPase.
    Epitope:
    Cytoplasmic domain
    Molecular Weight:
    112 kDa
    Control:
    Rat Brain Microsomal Prep. lysate.
    Presentation:
    Purified antibody in buffer containing 0.1M Tris-Glycine (pH7.4) 150mM NaCl and 0.05% NaN3.
    Storage Conditions:
    Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
    Gene Symbol:
    • ATP1A1
    • G00-119-711
    • Na
    • +K
    • MGC3285
    • MGC51750
    Quality Assurance:
    Routinely evaluated by Immunoprecipitation on rat brain microsomal prep. lysate.
    Antibody Category:
    Neuroscience
    Antibody Sub-Category:
    Ion Channels & Transporters
    Usage Statement:
    Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    Trade Name:
    Upstate (Millipore)
    Concentration:
    1 mg/mL
    Antibody Type:
    Polyclonal Antibody
    Format:
    Purified
    Host:
    Rabbit

    更多产品技术资讯，请访问密理博中国博客：http://blog.milliporechina.com

    Fusion protein containing residues 338-518 of the alpha-1 subunit, as deduced from the cDNA 详细描述见链接：http://www.millipore.com/catalogue/item/06-520

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