【HAV P2C-P3B】重组甲型肝炎病毒P2C-P3B蛋白

产品名称：【HAV P2C-P3B】重组甲型肝炎病毒P2C-P3B蛋白-Recombinant Hepatitis A Virus P2C-P3B

产品货号：HAV-230

产品规格：0.5mg///100ug///1mg

来源宿主：大肠杆菌中重组表达

保存建议：【HAV P2C-P3B】重组甲型肝炎病毒P2C-P3B蛋白-Recombinant Hepatitis A Virus P2C-P3BFive years frozen. One month in solution at room temperature.

背景资料：Forty-two antigenic domains were identified across the hepatitis A virus （HAV） polyprotein by using a set of 237 overlapping 20-mer synthetic peptides spanning the entire HAV polyprotein. Nineteen antigenic domains were found within the structural proteins， and 22 were found within the nonstructural proteins， with 1 domain spanning the junction of VP1 and P2A proteins. Five of these domains were considered immunodominant， as judged by both the breadth and the strength of their immunoreactivity. One domain is located within the VP2 protein at position 57-90 aa. A second domain， located at position 767-842 aa， contains the C-terminal part of the VP1 protein and the entire P2A protein. A third domain， located at position 1403-1456 aa， comprises the C-terminal part of the P2C protein and the N-terminal half of the P3A protein. The fourth domain， located at position 1500-1519 aa， includes almost the entire P3B， and the last domain， located at position 1719-1764 aa， contains the C-terminal region of the P3C protein and the N-terminal region of the P3D protein. Four of the five most immunoreactive domains are derived from small HAV proteins and/or encompass protein cleavage sites separating different HAV proteins.

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关键词：Recombinant Hepatitis A Virus P2C-P3B，【HAV P2C-P3B】重组甲型肝炎病毒P2C-P3B蛋白，HAV P2C