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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
- 保质期:
Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
- 英文名:
Recombinant Human Selenoprotein P (SEPP1) (U59S,U300S,U318S,U330S,U345S,U352S,U367S,U369S,U376S,U378S)
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 规格:
1mg/100μg/20μg
| 规格: | 1mg | 产品价格: | ¥13860.0 |
|---|---|---|---|
| 规格: | 100μg | 产品价格: | ¥3096.0 |
| 规格: | 20μg | 产品价格: | ¥1656.0 |
纯度:
Greater than 90% as determined by SDS-PAGE.基因名:
SEPP1Uniprot No.:
P49908别名:
Selenoprotein P; Selenoprotein P plasma 1; Selp; SeP; Sepp1; SEPP1_HUMAN种属:
Homo sapiens (Human)蛋白长度:
Full Length of Mature Protein来源:
Yeast分子量:
42.6 kDa表达区域:
20-381aa(U59S,U300S,U318S,U330S,U345S,U352S,U367S,U369S,U376S,U378S)氨基酸序列:
ESQDQSSLCKQPPAWSIRDQDPMLNSNGSVTVVALLQASSYLCILQASKLEDLRVKLKKEGYSNISYIVVNHQGISSRLKYTHLKNKVSEHIPVYQQEENQTDVWTLLNGSKDDFLIYDRCGRLVYHLGLPFSFLTFPYVEEAIKIAYCEKKCGNCSLTTLKDEDFCKRVSLATVDKTVETPSPHYHHEHHHNHGHQHLG_S_SELSENQQPGAPNAPTHPAPPGLHHHHKHKGQHRQGHPENRDMPASEDLQDLQKKLCRKRCINQLLCKLPTDSELAPRSSCCHCRHLIFEKTGSAITSQCKENLPSLCSSQGLRAEENITESCQSRLPPAASQISQQLIPTEASASSRSKNQAKKSESPSN蛋白标签:
N-terminal 6xHis-tagged产品提供形式:
Liquid or Lyophilized powder缓冲液:
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.货期:
3-7 business days注意事项:
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.功能:
Might be responsible for some of the Extracellular domain antioxidant defense properties of selenium or might be involved in the transport of selenium. May supply selenium to tissues such as brain and testis.内毒素:
Not test.SDS-PAGE:
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.LC-MS Image Description/Western Blot:
/Product types:
In Stock ProteinBiological_Activity:
/Research Areas:
OthersReconstitution:
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.Reference:
Conserved nucleotide sequences in the open reading frame and 3' untranslated region of selenoprotein P mRNA.Hill K.E., Lloyd R.S., Burk R.F.Proc. Natl. Acad. Sci. U.S.A. 90:537-541(1993)Function:
Might be responsible for some of the extracellular antioxidant defense properties of selenium or might be involved in the transport of selenium. May supply selenium to tissues such as brain and testis.风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验施一公团队又出新作!进一步解析人类 U2 snRNP 组装过程,提供癌症突变机制新见解
,并且人们对此知之甚少。17S U2 被认为是直接参与早期剪接体组装的人类 U2 snRNP 的功能形式。17S U2 snRNP 的核心成分包括 SF3b 配合物、SF3a 配合物、12S U2 核心、剪接因子 TAT-SF1 和 DDX46。体外实验也表明,SF3b 与 12S U2 核依次组装,形成一种被称为 15S 粒子的中间产物,最终形成 SF3a 复合物。然而,对组装这一过程的蛋白质因子却知之甚少。 最新的研究表明,具有 RNA 伴侣活性的 DDX42 可能是在 U2 snRNP 组装
浅析染色质免疫沉淀(ChIP)技术在 DNA 与蛋白质相互作用研究中的重要性
] Kim, D.H., et al., MicroRNA-directed transcriptional gene silencing in mammalian cells. Proc Natl Acad Sci U S A, 2008. 105(42): p. 16230-5. [29] Borchert, G.M., W. Lanier, and B.L. Davidson, RNA polymerase III transcribes human microRNAs. Nat Struct
。[11][12][13]真核生物的核糖核酸酶P中的RNA组分直到最近才被证明是核酶;[14]其蛋白质亚基自身对于底物tRNA的剪切只具有次要作用,[15]这些亚基可能是在核糖核酸酶P和核糖核酸酶MRP的其他功能(如基因转录和细胞周期)中发挥主要作用。[4][16] 参考文献 ^ 1.0 1.1 (英文)Guerrier-Takada C, Gardiner K, Marsh T, Pace N, Altman S. The RNA moiety of ribonuclease
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