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- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 保存条件:
We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃.
- 保质期:
Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
- 英文名:
Recombinant Human Complement receptor type 1 (CR1), partial
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 规格:
20μg
英文名称:
Recombinant Human Complement receptor type 1 (CR1), partial品名简称:
Recombinant Human CR1 protein, partial货号:
CSB-EP005932HU规格:
20μg价格:
1344LC-MS/Western Blot:
/SDS-PAGE:
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.纯度:
Greater than 90% as determined by SDS-PAGE.内毒素:
Not test生物活性:
/基因名:
CR1Uniprot No.:
P17927别名:
C3b/C4b receptor CD_antigen: CD35种属:
Homo sapiens (Human)蛋白长度:
Partial来源:
E.coli分子量:
48.4 kDa表达区域:
41-234aa氨基酸序列:
GQCNAPEWLPFARPTNLTDEFEFPIGTYLNYECRPGYSGRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCII蛋白标签:
N-terminal GST-tagged产品提供形式:
Liquid or Lyophilized powder缓冲液:
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.储存条件:
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.保质期:
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.货期:
3-7 business days注意事项:
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.功能1:
Mediates cellular binding of particles and immune complexes that have activated complement. (Microbial infection) Acts as a receptor for Epstein-Barr virus.功能2:
Mediates cellular binding of particles and immune complexes that have activated complement.; FUNCTION文献:
"Identification of distinct C3b and C4b recognition sites in the human C3b/C4b receptor (CR1, CD35) by deletion mutagenesis."Klickstein L.B., Bartow T.J., Miletic V., Rabson L.D., Smith J.A., Fearon D.T.J. Exp. Med. 168:1699-1717(1988)研究领域:
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- 作者
- 内容
- 询问日期
文献和实验CD35 分子 CD35 常用单克隆抗体或代号: TO5,E11;(CR1) 主要表达细胞: G,M,DC,B,NKsubRBC [M] 分子质量(kDa)和结构: p250(含CCP结构域) 功 能: 结合C3b和C4b,调理吞噬,红细胞免疫粘附,调节B细胞活化 CD35 Aka CR1, C3b and C4b receptor Mediates adherence
网络 二、I型补体受体(CD35) I型补体受体(CR1、C3b/C受体,又称CD35) 为单链穿膜糖蛋白,分子量160-260kDa。CRI有四种同种异型,其分子量与基因频率分别为,A:190kDa(0.83)、B:220kDa(0.16)、C:160kDa(0.01)和D:260kDa(0.002),但它们的功能相同。CR1广泛分布
对补体第三成分( C3)的受体,存在于多形核白血球、巨噬细胞、 B细胞、人 O型血的红细胞、哺乳动物的血小板中.在补体活化途径的第一途径,在抗原抗体复合体上是按 C1→ C4→ C2→ C3的顺序进行反应;第二途径是在血清中各种因子的存在下,譬如对细菌细胞壁等成分 C3进行反应。进行反应的 C3活化后,分为 C3a和 C3b,而 C3b可附着于抗原和细菌多形核白细胞(特别是嗜中性细胞)和巨噬细胞,通过 C3b受体对物质进行捕捉,经吞噬作用进入细胞内。 B细胞的补体
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