SOX9|SOX9蛋白|SOX9人蛋白|SOX9 Human

Chromatin Assembly and In Vitro Transcription Analyses for Evaluation of Individual Protein Activities in Multicomponent Transcriptional Complexes

transcriptional complexes have not been fully elucidated because of technical difficulties in using in vitro experimental systems. Previously we demonstrated that the DNA-binding transcription factor Sox9, HAT coactivator p300, and other regulatory factors (Smad

类器官培养与应用——垂体瘤类器官

人垂体肿瘤（human pituitary tumors, HPA）起源于垂体前叶的内分泌细胞，约占所有颅内肿瘤的 15%，通常被认为是良性肿瘤。然而在手术治疗中发现，30-40% 病例发生了局部的侵袭性行为【1】。垂体瘤分为功能性垂体瘤和无功能性垂体瘤，根据瘤细胞分泌的激素将功能性垂体瘤再进一步分为：泌乳素细胞腺瘤（PRL），生长激素细胞腺瘤（GH），促肾上腺皮质激素细胞瘤（ACTH），促甲状腺素细胞瘤（TSH），促性腺激素细胞瘤（LH/FSH）及混合瘤和未分类腺瘤。 目前，侵袭性垂体

Isolation of Fetal Gonads from Embryos of Timed-Pregnant Mice for Morphological and Molecular Studies

for isolation of embryonic gonads at different developmental stages from embryos of timed-pregnant mice. The isolated fetal gonads can be used for a variety of studies, such as organ culture, gene and protein expression. As examples of applications