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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
- 保质期:
12个月
- 英文名:
Recombinant Human Interleukin-15 (IL15)
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 规格:
10ug/20ug/50ug/100ug/200ug/500ug/1mg
| 规格: | 10ug | 产品价格: | ¥69.0 |
|---|---|---|---|
| 规格: | 20ug | 产品价格: | ¥139.0 |
| 规格: | 50ug | 产品价格: | ¥209.0 |
| 规格: | 100ug | 产品价格: | ¥349.0 |
| 规格: | 200ug | 产品价格: | ¥419.0 |
| 规格: | 500ug | 产品价格: | ¥559.0 |
| 规格: | 1mg | 产品价格: | ¥699.0 |
Research Areas
MetabolismUniprot ID
P40933Gene Names
IL15Alternative Name(s)
IL 15; IL-15; IL15; IL15_HUMAN; Interleukin 15; Interleukin-15; Interleukin15; MGC9721Lead Time
3-7 business daysOrganism
Homo sapiens (Human)Source
E.coliExpression Region
49-162aaProtein Length
Full Length of Mature ProteinTag Info
N-terminal 6xHis-taggedTarget Protein Sequence
NWVNVISDLKKIEDLIQSMHIDATLYTESDVHPSCKVTAMKCFLLELQVISLESGDASIHDTVENLIILANNSLSSNGNVTESGCKECEELEEKNIKEFLQSFVHIVQMFINTSMW
16.8 kDaPurity
Greater than 90% as determined by SDS-PAGE.Form
Liquid or Lyophilized powderBuffer
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Interleukin 15 (IL-15) has been described as a cytokine with biologic functions similar to those of IL-2. IL-2 and IL-15 utilize a receptor composed of three subunits: IL-2 receptor β-chain, the y-chain (βc) shared by IL-15, IL-2, IL-4, IL-
近几年,以 T 细胞为靶点的免疫治疗策略的研究一直居于肿瘤免疫治疗研究热点榜高位,当大家都想在这个领域分一杯羹时,新的尝试开始逐渐挤入热度的核心,其中不乏以 NK 细胞为靶点的治疗方法的探索。与 T 细胞的研究相比,NK 细胞相关研究出了「抄作业」之外,还有什么特殊之处呢? IL15 是 NK 细胞发育所必须的细胞因子 NK 细胞又称自然杀伤细胞,属于天然免疫系统的核心细胞,是机体内重要的免疫细胞。NK 细胞是人体抵抗癌细胞和病毒感染的第一道防线,可非特异性直接杀伤肿瘤细胞,这种天然杀伤
有氧运动真的能抗癌!Cancer Cell:一周 5 次、每次 30 分钟,就可助力免疫系统杀死癌细胞
癌化疗效果 近年来,IL15 信号通路在肿瘤中的作用日益清晰,科学家已经尝试通过直接注射 IL15 治疗癌症,但却会引发严重的系统性炎症损伤。 IL15 与 T 细胞或 NK 细胞等免疫细胞存在蛋白与受体蛋白的「锁钥相互作用」,即 IL-15 与 IL-15Rα 相互作用,激活受体细胞。基于此,诺华制药开发了一种「超级激动剂」——NIZ985。NIZ985 能够增强 IL-15/IL-15Rα 信号通路,同时降低潜在的炎症反应。相关研究尚未在胰腺癌患者中进行大规模检测。 吉西他滨和白蛋白
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