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L-690488
CAS No. : 142523-14-6
MCE 国际站：L-690488
产品活性：L-690488 是一种 L-690330 的前体，也是一种选择性的肌醇单磷酸酶 (IMPase) 抑制剂。L-690488 比 L-690330 具有更有效的细胞穿透能力。
研究领域：Metabolic Enzyme/Protease
作用靶点：Phosphatase
In Vitro: The effects of L-690488 are studied in cholinergically (carbachol)-stimulated rat cortical slices and Chinese hamster ovary cells stably transfected with the human muscarinic m1 receptor (m1 CHO cells). The EC50 values of L-690488 are 3.7 μM and 1.0 μM in rat cortical slices and m1 CHO cells, respectively). The time course and maximum accumulation of [3H] CMP-PA in L-690488-treated m1 CHO cells is similar to lithium but L-690488 is again much more potent (EC50 values of 3.5 μM and 0.52 mM for L-690488 and lithium, respectively).
L-690488 attenuates the carbachol-induced elevation of inositol 1,4,5-trisphosphate and inositol 1,3,4,5-tetrakisphosphate in m1 CHO cells. That these effects of L-690488 on the phosphatidylinositol (Pl) cycle are indeed due to inositol depletion.
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文献和实验左旋茶氨酸 L-theanine 即谷酰基乙胺。是从茶叶中发现的（ Y． Saka-to， 1950）。与谷氨酸同样机制合成。
L-DOPA (L-3,4-Dihydroxyphenylalanine)
The nonprotein amino acid, 3,4-dihydroxyphenylalanine (L -DOPA) (Fig. 1) is present in high concentrations (about 3–6%) in Mucuna spp. The in vitro addition of L -DOPA to the red blood cells from individuals deficient in glucose 6-phosphate
L-Mimosine (-(3-Hydroxy-4-Pyridone-1-yl)-L-Alanine)
L -mimosine is a nonprotein amino acid. Despite the consideration of Leucaena leucocephala as a promising alternate source of protein for fodder, the presence of mimosine to the extent of 2% to 10% dry matter in the leaf and 2% to 5% dry
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