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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
1801333-55-0
- 规格：
10 mM * 1 mL/1 mg/5 mg/10 mg/25 mg/50 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥1007.0 |
|---|---|---|---|
| 规格： | 1 mg | 产品价格： | ￥600.0 |
| 规格： | 5 mg | 产品价格： | ￥997.0 |
| 规格： | 10 mg | 产品价格： | ￥1400.0 |
| 规格： | 25 mg | 产品价格： | ￥2397.0 |
| 规格： | 50 mg | 产品价格： | ￥4100.0 |
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PF-06952229
CAS No. : 1801333-55-0
MCE 国际站：PF-06952229
产品活性：PF-06952229 是一种强效、选择性和口服的 TGFbR1 抑制剂。PF-06952229 与 TGFbR1 特异性结合，阻止 TGFbR1 介导的信号转导。PF-06952229 是一种很有前途的抗肿瘤试剂 (antineoplastic agent)，主要用于研究实体瘤，尤其是转移性乳腺癌。
研究领域：TGF-beta/Smad
作用靶点：TGF-β Receptor
In Vivo: PF-06952229 (oral gavage; 30 mg/kg; twice daily; 21 days) combines with Palbociclib 21 days results in an improved inhibition of pSMAD2 in the MCF7 ER+ xenograft breast cancer tumor model. This combination also leads to a significant increase in survival relative to PF-06952229 monotherapy.
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文献和实验日本VESSEL（威威）GT-P6EXD,GT-P6EXD(A
4TS,GT-S4TR GT-S5TFG/S5TFB/S5TFR/S5TG/S5TB/S5TR/S5TR/S5TS,GT-1600VP/1600VPL/1600VPH/1600VPHL GT-3800VP/3800V/3800VL/3900VL/4800VL,GT-2000PF/2500PF/2500LF/3800PF/3800LF/4200PF GT-4200LF,GT-S55R,GT-S650/P6IIZ/S600C/P8II/P12
, go to the hood, put paraformaldehyde powder in the tube, close it-then weigh the tube again. Adjust water added as appropriate to yield 8% solution. No chance of breathing paraformaldehyde...) -Heat to 55 to 60 degrees in water bath. -Add 24 drops
-4.5. Freund M, Carol B. Factors Affecting Haemocytometer Counts of Sperm Concentration in Human Semen. Journal of Reproductive Fertility 1964; 8: 149-55.6. Nielsen LK, Smyth GK, Greenfield PF. Hemacytometer Cell Count Distribution: Implications of Non-Poisson
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