- ￥1500
- DSHB
- America
- PCR-ZSCAN12-1A9-Concentrate 0.1 ml
- 2025年07月14日
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- 英文名：
ZSCAN12; Zinc finger and SCAN domain containing 12
- 库存：
999
- 供应商：
博奥派克
- 规格：
Concentrate 0.1 ml
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文献和实验Gene Editing in One‐Cell Embryos by Zinc‐Finger and TAL Nucleases
editing using sequence‐specific nucleases. Sequence‐specific nucleases are composed of a domain that binds to the target gene via zinc‐finger or TAL effector‐based DNA recognition motifs. The DNA binding part is fused to the nonspecific nuclease domain
-binding specificities. We used these zinc fingers as modular building blocks in the construction of novel, sequence-specific DNA-binding proteins. Fusion of these zinc-finger proteins with either a transcriptional activation or repression domain yielded
Protocol online). All DNAs used as templates for PCR were SP1 variants containing specific zinc-finger -helices selected and characterized in our laboratory8, 10, 12 . These templates were cloned and sequenced in pMalc2 (New England Biolabs, Beverly, MA
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