- 询价
- 近岸蛋白(Novoprotein)
- DRA47
- 2026年07月11日
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- 文献和实验
- 技术资料
- 英文名：
Recombinant 2019-nCoV S1 Protein (C-6His)
- 保存条件：
Reconstituted protein solution should be stored at ≤ -20°C.
- 规格：
1mg
Recombinant 2019-nCoV S1 Protein (C-6His)
Catalog #: DRA47 Derived From: Human Cells
Description:
Recombinant 2019-nCoV S1 Protein is produced by our Mammalian expression system and the target gene encoding Val16-Arg685 is expressed with a 6His tag at the C-terminus.
Accession: QHD43416.1
Names(Known as): S1 protein; 2019-nCoV S1 protein; coronavirus S1 Protein; cov S1 Protein
Quality Control:
Mol Mass: 75.8kDa AP Mol Mass: 100-130kDa, reducing conditions
Purity: Greater than 95% as determined by reducing SDS-PAGE.
Formulation:
Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Shipping:
The product is shipped on dry ice pack.
Upon receipt, store it immediately at the temperature listed below.
Storage:
Reconstituted protein solution should be stored at ≤ -20°C.
Purification:
Affinity purification chromatography.
Immunoreactivity:
N.A.
Application:
Immunogen, calibrator or standard.
Background:
Protein S (PROS1) is glycoprotein and expressed in many cell types supporting its reported involvement in multiple biological processes that include coagulation, apoptosis, cancer development and progression, and the innate immune response. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2, DPP4, CEACAM etc. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
FOR RESEARCH OR FURTHER MANUFACTURING USE ONLY
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文献和实验Protein C (PC) is a 62-kDa vitamin K-dependent plasma zymogen which, after activation to serine protease, plays an important role in the physiologic regulation of blood coagulation. Given that PC is one of the major naturally
为肌肉调节蛋白质。分子量约 14万，在肌原纤维 A带中的 A丝上，显示 43纳米周期，常混存于肌球蛋白的材料中。为 G． Offer（ 1972）所发现。
Protein Extraction From Mammalian Tissues
For Western blotting and coimmunoprecipitation (coIP), protein samples must be extracted from tissues. The protocol described in this chapter has been used to extract clock proteins from mammalian tissues as diverse as liver, kidney
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