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- 详细信息
- 技术资料
- 保存条件:
4°C, protect from light
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- CAS号:
611-40-5
- 规格:
10 mM * 1 mL/5 mg/10 mg/50 mg/100 mg
| 规格: | 10 mM * 1 mL | 产品价格: | ¥509.0 |
|---|---|---|---|
| 规格: | 5 mg | 产品价格: | ¥500.0 |
| 规格: | 10 mg | 产品价格: | ¥650.0 |
| 规格: | 50 mg | 产品价格: | ¥1300.0 |
| 规格: | 100 mg | 产品价格: | ¥1950.0 |
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Tectoridin
CAS No. : 611-40-5
MCE 国际站:Tectoridin
产品活性:Tectoridin 是一种从 Maackia amurensis 分离的异黄酮。Tectoridin 是一种植物雌激素,可激活雌激素和甲状腺激素受体。Tectoridin 通过 ER 依赖性基因组途径和 GPR30 依赖性非基因组途径发挥雌激素作用。
研究领域:Vitamin D Related/Nuclear Receptor
作用靶点:Estrogen Receptor/ERR
In Vitro: Tectoridin scarcely binds to ER alpha as compared to 17beta-estradiol and genistein.
Tectoridin induceds potent estrogenic effects, namely recovery of the population of cells in the S-phase after serum starvation, transactivation of the estrogen response element, and induction of MCF-7 cell proliferation.
Tectoridin induces estrogenic effect, and this effect is severely abrogated by treatment with U0126 ( MEK1/2 inhibitor). Tectoridin promotes phosphorylation of ERK1/2, but does not affect phosphorylation of ER alpha at Ser (118). It also increases cellular accumulation of cAMP.
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