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- MedChemExpress(MCE)
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- HY-N0564
- 2025年12月05日
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- 技术资料
- 保存条件：
4°C, protect from light
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
88206-46-6
- 规格：
10 mM * 1 mL/5 mg/10 mg/25 mg/50 mg/100 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥440.0 |
|---|---|---|---|
| 规格： | 5 mg | 产品价格： | ￥400.0 |
| 规格： | 10 mg | 产品价格： | ￥560.0 |
| 规格： | 25 mg | 产品价格： | ￥960.0 |
| 规格： | 50 mg | 产品价格： | ￥1440.0 |
| 规格： | 100 mg | 产品价格： | ￥2160.0 |
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Notopterol
CAS No. : 88206-46-6
MCE 国际站：Notopterol
产品活性：Notopterol 是从 N. incisum 提取的香豆素。Notopterol 诱导细胞凋亡，具有解热，缓解疼痛和抗炎作用。Notopterol 有用于急性髓细胞性白血病 (AML) 的潜力。
研究领域：Apoptosis
作用靶点：Apoptosis
In Vitro: notopterol (5, 10, 20, 40, 60 μM; for 48 hours) promotes cell apoptosis in a dose-dependent manner.
notopterol (10, 20, 40, 60 and 80 μM; 24-120 hours) inhibits the proliferation of HL-60 cells in a concentration-dependent manner.
Notopterol (5, 10, 20 and 40 μM; for 48 hours) induces G0/G1 phase arrest associated with cell-cycle proteins in HL-60 cells.
Notopterol (5, 10, 20 and 40 μM; for 48 hours) increases the expression of Bax and decreased the expression of Bcl-2 and Mcl-1 in HL-60 cells after 48-hr treatment. Moreover, Notopterol also promotes the cleavage of caspase 9, caspase 3 and PARP.
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