m-PEG5-CH2COOH,16142-03-3

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m-PEG5-CH2COOH

CAS No. : 16142-03-3

MCE 国际站：m-PEG5-CH2COOH

产品活性：m-PEG5-CH2COOH 是一种不可降解 (non-cleavable) 的 ADC linker，用于抗体偶联活性分子 (ADC) 的合成。m-PEG5-CH2COOH 也是一种基于 PEG 的 PROTAC linker，可用于 PROTAC 的合成。

研究领域：Antibody-drug Conjugate/ADC Related  |  PROTAC

作用靶点：ADC Linker  |  PROTAC Linkers

In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

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