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- Cell Signaling Technology
- USA
- 77046S
- 2025年07月12日
- W
- 兔
- H
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-20℃
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多克隆
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文献和实验To engineer or manipulate antibody or Fv-based molecules, isolation of the V region of the antibodies is necessary. A number of strategies can be adopted for amplification; one such approach is to use subgroup-specific oligonucleotides
Expression of Antibody Fusion Proteins in Mammalian Cells
, a toxin, enzyme, cytokine, or antibody constant region. Progress in this area is summarized in recent reviews (2 ,3 ).
Tailoring Natural Effector Functions: Antibody Engineering Beyond Humanization
. Some are based on fusions of murine variable regions with human constant region, called chimeric antibodies. Others are more sophisticated being “humanized” from their mouse monoclonal parent molecule, whereas more recently full human antibodies from phage
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