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AFP (Alpha Fetoprotein) (Hepa

tocellular/Germ Cell Tumor Marker) Antibody - Without BSA and Azide
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  • $495
  • Leading Biology
  • 2025年10月11日
  • IHC-P, IF, FC
  • Mouse
  • Human, Monkey, Pig, Dog
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 亚型

      Mouse / IgG2a, kappa

    • 保存条件

      Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

    • 克隆性

      单克隆

    • 适应物种

      Human, Monkey, Pig, Dog

    • 库存

      100

    • 宿主

      Mouse

    • 应用范围

      IHC-P, IF, FC

    • 规格

      100 μg

    Prouduct: We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality AFP (Alpha Fetoprotein) (Hepatocellular/Germ Cell Tumor Marker) Antibody - Without BSA and Azide. Functiong: Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties. Summary: It recognizes an oncofetal glycoprotein with a single chain of 70kDa, which is identified as alpha-fetoprotein (AFP) (ISOBM TD-2 workshop). This MAb is highly specific to AFP and shows no cross-reaction with other oncofetal antigens or serum albumin. AFP is normally synthesized in the liver, intestinal tract, and yolk sac of the fetus. Antibody to AFP has been shown to be useful in detecting hepatocellular carcinomas (HCC) and germ cell neoplasms, especially yolk sac tumors.

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    图标文献和实验
    相关实验
    • 细思极恐:甲胎蛋白异常升高,竟然揪出这种癌症!

      -fetoprotein-producing non-germ cell tumours of the female genitaltract. Eur J Cancer.2010,46:1317-1322.[5]Ishikura H,Fukasawa Y,Ogasawara K,et al.An AFP-producing gastric carcinoma with features of hepatic differentiation.A case report. Cancer.1985,56:840-848

    • Gene Therapy Vectors Harboring AFP Regulatory Sequences: Preparation of an Adenoviral Vector

      by introducing a cytotoxic gene under the control of transcriptional regulatory sequences of the a-fetoprotein (AFP) gene. The expression of the therapeutic gene should be limited to AFP-positive cells (i.e., HCC), so that only tumor cells will be eliminated

    • 甲胎蛋白(AFP)具有抑制PTEN的生物学功能

      北京大学和海南医学院联合对肝癌细胞特异性标志物甲胎蛋白(AFP)进行长时间的研究,发现AFP具有抑制PTEN的生物学功能,导致肝癌细胞耐受全反式维甲酸诱导的凋亡,这是AFP新功能的发现。近日以题为“Alpha-fetoprotein:  a  new  member  of  intracellular  signal  molecules  in  regulation  of  the  PI3K/AKT  signaling  in  human  hepatoma 

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