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AFP (Alpha Fetoprotein) (Hepa

tocellular/Germ Cell Tumor Marker) Antibody
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  • $495
  • Leading Biology
  • 2025年10月07日
  • IHC, IF, FC
  • Mouse
  • Human, Monkey, Pig, Dog
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 亚型

      Mouse / IgG2a, kappa

    • 保存条件

      Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

    • 克隆性

      单克隆

    • 适应物种

      Human, Monkey, Pig, Dog

    • 库存

      100

    • 宿主

      Mouse

    • 应用范围

      IHC, IF, FC

    • 规格

      7 ml

    Prouduct: We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality AFP (Alpha Fetoprotein) (Hepatocellular/Germ Cell Tumor Marker) Antibody. Functiong: Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties. Summary: It recognizes an oncofetal glycoprotein with a single chain of 70kDa, which is identified as alpha-fetoprotein (AFP) (ISOBM TD-2 workshop). This MAb is highly specific to AFP and shows no cross-reaction with other oncofetal antigens or serum albumin. AFP is normally synthesized in the liver, intestinal tract, and yolk sac of the fetus. Antibody to AFP has been shown to be useful in detecting hepatocellular carcinomas (HCC) and germ cell neoplasms, especially yolk sac tumors.

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    图标文献和实验
    相关实验
    • 甲胎蛋白(α-fetoprotein

      甲胎蛋白(α-fetoprotein,αFP或AFP)主要在胎儿肝中合成,分子量6.9万,在胎儿13周AFP占血浆蛋白总量的1/3。在妊娠30周达最高峰,以后逐渐下降,出生时血浆中浓度为高峰期的1%左右,约40mg/L,在周岁时接近成人水平(低于30μmg/L)。   甲胎蛋白在产妇羊水或母体血浆中AFP可用于胎儿产前监测。如在神经管缺损、脊柱裂、无脑儿等时,AFP可由开放的神经管进入羊水而导致其在羊水中含量显著升高。胎儿在宫腔内死亡、畸胎瘤等先天缺陷亦可有羊水中AFP

    • α-胎儿蛋白 α-fetoprotein

         缩写 AFP.为仅在胎儿血清中存在的蛋白质(成人血清中没有),也称为胎球蛋白( fetuin)、α 1 -胎儿球蛋白(α 1 -fetoglobulin)、后清蛋白。在电泳实验中可在α -球蛋白区域(有的动物在β -球蛋白区域)找到。是在胎儿的肝脏中合成的。关于分子的性质,人的分子量为 6.46万, S20 , w=4.5S, D20 , w=6.18, pI为 pH=4.8,由单链多肽所成;而鼠的是由 586个氨基酸所成,其结构由三个( 1— 193, 194— 385

    • MicroRNA Expression Profiling by Bead Array Technology in Human Tumor Cell Lines Treated with Interferon-Alpha-2a

      microRNA detection platform to identify genes that are induced by IFNα in hepatoma- or melanoma-derived human tumor cell lines. Despite the enormous differences in expression levels between these models, we were able to identify microRNAs

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