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Dio-1 Antibody

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  • $495
  • Leading Biology
  • APR00143G
  • 2025年10月09日
  • WB
  • Rabbit
  • Human, Mouse
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 亚型

      Rabbit IgG

    • 保存条件

      Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

    • 适应物种

      Human, Mouse

    • 库存

      100

    • 宿主

      Rabbit

    • 应用范围

      WB

    • 靶点

      Dio-1

    • 规格

      100 μg

    Prouduct: We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Dio-1 Antibody. Functiong: Required for early embryonic stem cell development (By similarity). Putative transcription factor, weakly pro-apoptotic when overexpressed. Summary: Apoptosis plays an important role in many cellular processes. Dio-1 (Death Inducer-O bliterator-1), a putative transcription factor, has been indicated to function in the onset of apoptosis. Dio-1 expression is upregulated when an apoptosis is detected. It translocates to the nucleus, and activates apoptosis during limb development. Dio-1 expression can be suppressed by caspase inhibitors and Bcl-2 expression.

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    图标文献和实验
    相关实验
    • DIO 小鼠特点及造模和饲养注意事项

      外观:因为高脂饮食,毛发看起来有些「油腻」。 活动:因 DIO 的肥胖表型,多数小鼠看起来比较「慵懒」,不爱动。 脱毛:因 B6 品系的特性,容易出现理毛导致的脱毛,需关注是否有继发皮肤炎症反应。 运输应激:DIO 小鼠在经历运输后容易出现体重降低的情况。根据友商资料和我们的历史数据,运输后 DIO 平均体重减轻在 10%-15%。一般需要经过 2 周左右的适应性饲养,体重可以恢复到出库水平。 打架现象:因雄鼠的天性问题,可能会出现打架的情况,建议不要将不同笼小鼠进行混装。 B6 小鼠会

    • Generation of Antibody Molecules Through Antibody Engineering

      been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional

    • The Antibody Molecule

      The importance of antibody molecules was first recognized in the 1890s, when it was shown that immunity to tetanus and diphtheria was caused by antibodies against the bacterial exotoxins (1 ). Around the same time, it was shown that antisera

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