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- 文献和实验
- 技术资料
- 保存条件:
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
- 适应物种:
Human, Mouse, Rat
- 库存:
100
- 宿主:
Rabbit
- 应用范围:
WB
- 规格:
100 μl
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文献和实验抗淋巴细胞血清(ALS) anti-lymphocyteserum
对抗淋巴细胞特异性抗原的异种动物抗血清,简称ALS。例如将小鼠的淋巴细胞(或从淋巴细胞抽提出的抗原物质)给兔注射时,兔便形成对抗小鼠淋巴细胞的抗体。在这种血清中既含有与淋巴细胞以外的细胞起反应的抗体,又含有仅仅与淋巴细胞起反应的抗体。通过用适当的方法将前者吸收清除掉,可得到抗淋巴细胞血清。抗淋巴细胞血清主要保持对 T细胞的反应性,对 B细胞起反应的抗血清不能简易制成。将抗淋巴细胞血清给动物注射时,既可看到血液中的淋巴细胞减少,又出现细胞性免疫及对抗许多抗原的抗体形成下降。
Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
The importance of antibody molecules was first recognized in the 1890s, when it was shown that immunity to tetanus and diphtheria was caused by antibodies against the bacterial exotoxins (1 ). Around the same time, it was shown that antisera
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