Ready-to-use 3D Human Calvaria

Ready-to-use 3D Human Calvarial Osteoblast Spheroid Kit说明：

       Bone is a living organ maintained by osteoblasts and osteoclasts. Osteoblasts, the bone-forming cells, secrete bone matrix such as type I collagen, while they remain exclusively as an organized tight epithelium to separate the bone extracellular matrix from general extracellular fluid. As matrix grow, osteoblasts are incorporated into the matrix as osteocytes, which communicate with each other and surface layer osteoblasts through cell processes that run within canaliculi in the matrix. The complex interactions between cell-cell and cell-ECM are critical for the process of bone formation and mineralization. Furthermore, these complex interactions are strictly dependent on the three-dimensional (3D) environment. To better approximate the in vivo condition, ScienCell has developed a highly innovative ready-to-use 3D osteoblast spheroid kit (SP3D-HCOS) in which cells maintain direct cell-cell and cell-ECM interactions in all three dimensions. With ScienCell’s Ready-to-use 3D spheroid kit, researchers can generate more physiologically relevant data from 3D spheroid culture in 24 hours after thawing, without encountering the long and complex workflow of 3D culture.
骨是由成骨细胞和破骨细胞维持的活器官。成骨细胞，即骨形成细胞，分泌骨基质如I型胶原，但它们仅作为一个有组织的紧密的上皮细胞，将骨细胞外基质与一般的细胞外液体分离。随着基质的生长，成骨细胞以骨细胞的形式与基质结合，并通过基质内小管内的细胞过程与表层成骨细胞相互沟通。细胞-细胞和细胞- ecm之间的复杂相互作用对骨形成和矿化过程至关重要。此外，这些复杂的相互作用严格依赖于三维(3D)环境。为了更好地接近体内条件，ScienCell开发了一种高度创新的3D成骨细胞椭球体试剂盒(SP3D-HCOS)，在该试剂盒中，细胞在所有三维空间中维持细胞与细胞和细胞外基质的直接相互作用。利用ScienCell的3D球体工具箱，研究人员可以在解冻后的24小时内，从3D球体培养中获得更多的生理相关数据，而不需要面对漫长而复杂的3D培养工作流程。
 

Catalog No.	SP3D-4600
Country of Manufacture	United States
Product Code	SP3D-HCOS
Size/Quantity
Product Use	SP3D-HCOS is for research use only. It is not approved for human or animal use, or application in clinical or in vitrodiagnostic procedures.
Storage
Shipping Info	SP-4600, 3D-4652, 0010, and 0583 are shipped on dry ice. 3D-4601, and [0343 (or) 0353 (or) 0383] are shipped at room temperature.