重组人IFN-α1a北京品牌

特别提示：包括重组人IFN-α1a在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人IFN-α1a
英文名称：Recombinant Human Interferon-alpha1a
产品货号：GS4670
产品规格：20μg

分子量：Approximately 19.5kDa,a single non-glycosylated polypeptide chain containing 167 amino acids.
储存条件：冷冻（-20℃）

概述

IFN-αs are proteins secreted by leukocyte.They are mainly involved in innate immune response against viral infection.The IFN-α family has 13 subtypes and 23 different variants.The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids.All IFN-α subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable.Many IFN-alpha subtypes differ in their sequences at only one or two positions.Naturally occurring variants also include proteins truncated by 10 amino acids at the carboxy-terminal end.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格
 

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞97%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The specific activity determined by an anti-viral assay is no less than 1.0×108 IU/mg.
成分	Lyophilized from a 0.2μmfiltered solution in PBS,pH 7.4,containing 3%Mannitol,5%Trehalose,0.05%Tween-80.
内毒素	Less than 0.1 EU/μg of rHuIFN-α1a as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	MCDLPETHSL DNRRTLMLLA QMSRISPSSC LMDRHDFGFP QEEFDGNQFQ KAPAISVLHE LIQQIFNLFT TKDSSAAWDE DLLDKFCTEL YQQLNDLEAC VMQEERVGET PLMNADSILA VKKYFRRITL YLTEKKYSPC AWEVVRAEIM RSLSLSTNLQ ERLRRKE

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